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From: "George Irvine" <girvine@be*.ne*>
To: "Esat Atikkan" <atikkan@ya*.co*>, "Bruce R. Wienke" <brw@la*.go*>,
     ,
Subject: RE: FYI: RGBM WKPP/Irvine Test Deco Profile Comparison
Date: Tue, 12 Mar 2002 06:34:04 -0500
Esat, I did not see the origination of this discussion, but from what is
here , you are correct about what we do and to answer your question, Yes, we
do the blood studies and consider them to be our best indicator. So far, in
bloodwork, we are coming out with no indicators of any problems according to
the (Navy) doctors. We run before and after and then wait and do them again
later. Duke U is running similar studies on us now that will last quite some
time. In addition to the studies you mention, we are also looking for other
makers of DCS injury, or any injury.

-----Original Message-----
From: Esat Atikkan [mailto:atikkan@ya*.co*]
Sent: Monday, March 11, 2002 7:25 PM
To: Bruce R. Wienke; deco@de*.or*; techdiver@aquanaut.com
Subject: Re: FYI: RGBM WKPP/Irvine Test Deco Profile Comparison



has anyone looked at hematological & bichemical
parameters following these dives:
Crit, [Hb], plasma osmolarity, RBC fragility come to
mind as do plasma volume changes.

This would B fertile ground to assess the oxidative
stress of such dives, wh/, over the long haul, may B
more significant than the putative bubble problems.

I think Irvine & co deal w/ oxidative stress through
supplements of Vit E & C, wh/ would ameliorate the SOD
depletion, particularly the Cu/Zn SOD of the RBCs.

However, the peroxinitrate relaxation mediated
comprimise of vascular endothelial integrity does come
to mind as an area needing study.

If I recollect correctly this was studied & published
(Undersea Hyperbar Med in the late 90's does come to
mind).  how it applies to the dives modelled here
would be of interest.

Safe bubbles

Esat Atikkan

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