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Date: Mon, 11 Mar 2002 18:12:40 -0700
To: Esat Atikkan <atikkan@ya*.co*>, deco@de*.or*,
From: "Bruce R. Wienke" <brw@la*.go*>
Subject: Re: FYI: RGBM WKPP/Irvine Test Deco Profile Comparison
  Yes.

   Would be very interesting indeed -- this info needs folding into
 diving on the envelope. Especially considering the stress.

    We take Vits. exercise, and are in great shape here at/on
 LANL D-team, and will soon wet test 400/30 with He on way up (not
 nitrox switches that George uses).  Our dives are almost 90% He
 these days -- we avoid N2 as much as possible. We are highly DCI absent
 on RGBM schedules.  Bottom line -- deep stops are safe, cost effective,
 and time saving.  Even if "arbitrarily" built up from Haldane.

    Can't accurately quantify such complex biochemistry, vascularity
 and related phenomenon, but such in coarse grain deco planners enter thru
bub
 distribution, perfusion dilatation, etc., and possibly oxygen sat.  If you
 have data linked to DCI, we might be able to say something?


 BW



>has anyone looked at hematological & bichemical
>parameters following these dives:
>Crit, [Hb], plasma osmolarity, RBC fragility come to
>mind as do plasma volume changes.
>
>This would B fertile ground to assess the oxidative
>stress of such dives, wh/, over the long haul, may B
>more significant than the putative bubble problems.
>
>I think Irvine & co deal w/ oxidative stress through
>supplements of Vit E & C, wh/ would ameliorate the SOD
>depletion, particularly the Cu/Zn SOD of the RBCs.
>
>However, the peroxinitrate relaxation mediated
>comprimise of vascular endothelial integrity does come
>to mind as an area needing study.
>
>If I recollect correctly this was studied & published
>(Undersea Hyperbar Med in the late 90's does come to
>mind).  how it applies to the dives modelled here
>would be of interest.
>
>Safe bubbles
>
>Esat Atikkan
>
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