Mailing List Archive

Mailing List: techdiver

Message Display

Jason,

It had to do with the lack of research data and concerns about solubility
effects with argon.  Most algorithms just look at the diffusion rates
and perfusion, which works well with Nitrogen and Helium, as the solubilities
are not that dissimiliar.

However, argon is another story as to solubility.  In the uptake and
distribution of anesthesic agents, solubility plays a major role (as
can be seen in the establishment of anesthesia with Enflurane and Isoflurane,
different solubilities, same molecular weights and diffusion rates.)

The problem is, we do not know how to "adjust" the models to accurately
take into account this solubility factor.  

John

Navigate by Author: [Previous] [Next] [Author Search Index]
Navigate by Subject: [Previous] [Next] [Subject Search Index]

[Send Reply] [Send Message with New Topic]

[Search Selection] [Mailing List Home] [Home]