This is a multi-part message in MIME format. ------=_NextPart_000_0282_01BFB50D.3D1A4F80 Content-Type: text/plain; charset="iso-8859-1" Content-Transfer-Encoding: quoted-printable Haas this professor written up & submitted his research? Do you have the = citation for it, by any chance? If not, can you remember his first name, and what institution he's = affiliated with? Thanks, Rich L ----- Original Message -----=20 From: Aznan=20 To: techdiver@aquanaut.com=20 Sent: Monday, May 01, 2000 7:17 AM Subject: antioxidants Had some problem with first post, here's a repeat. =20 Have recently attended a presentation on the above by a Prof Halliwell. I would like to run it and related queries,=20 by the list for opinions. Superoxide anion damage to DNA was tracked by tracing 8OH deoxy Guanine, in urine. =20 1 Subjects were given a commercially available antioxidant, 8OH dG was found in increased levels and study terminated at 2 weeks. =20 2 Same set of subjects were given 500gm of raw tomatoes, {once a day} 8OH dG levels decreased and leveled off. Study = terminated. =20 3 When asked, he said that persons exposed to hyperbaric oxygen showed an initial increase in degradative products, but levels gradually decreased to pre-exposure levels. Time line not mentioned. =20 Aside, my questions are:- =20 Commercially available preparations of SOD, Catalase and Glutathione Peroxidase don't make it the cellular level because of protease action and stomach pH, and are therefore not worth crap? =20 If I'm planning preventive anti-ox therapy of vit E, C, Selenium etc do I plan according to Ox Tox % per dive day or cumulative ox tox per dive mission, or should I just go mega dose or saturation? =20 Any feedback on pine bark extract? =20 Omar ------=_NextPart_000_0282_01BFB50D.3D1A4F80 Content-Type: text/html; charset="iso-8859-1" Content-Transfer-Encoding: quoted-printable <!DOCTYPE HTML PUBLIC "-//W3C//DTD HTML 4.0 Transitional//EN"> <HTML><HEAD> <META content=3Dtext/html;charset=3Diso-8859-1 = http-equiv=3DContent-Type> <META content=3D"MSHTML 5.00.2314.1000" name=3DGENERATOR> <STYLE></STYLE> </HEAD> <BODY bgColor=3D#ffffff> <DIV><FONT size=3D2>Haas this professor written up & submitted his = research?=20 Do you have the citation for it, by any chance?</FONT></DIV> <DIV> </DIV> <DIV><FONT size=3D2>If not, can you remember his first name, and what = institution=20 he's affiliated with?</FONT></DIV> <DIV> </DIV> <DIV><FONT size=3D2>Thanks,</FONT></DIV> <DIV> </DIV> <DIV><FONT size=3D2>Rich L</FONT></DIV> <DIV> </DIV> <BLOCKQUOTE=20 style=3D"BORDER-LEFT: #000000 2px solid; MARGIN-LEFT: 5px; MARGIN-RIGHT: = 0px; PADDING-LEFT: 5px; PADDING-RIGHT: 0px"> <DIV style=3D"FONT: 10pt arial">----- Original Message ----- </DIV> <DIV=20 style=3D"BACKGROUND: #e4e4e4; FONT: 10pt arial; font-color: = black"><B>From:</B>=20 <A href=3D"mailto:bbqchic@si*.co*.sg*" = title=3Dbbqchic@si*.co*.sg*>Aznan</A>=20 </DIV> <DIV style=3D"FONT: 10pt arial"><B>To:</B> <A=20 href=3D"mailto:techdiver@aquanaut.com"=20 title=3Dtechdiver@aquanaut.com>techdiver@aquanaut.com</A> </DIV> <DIV style=3D"FONT: 10pt arial"><B>Sent:</B> Monday, May 01, 2000 7:17 = AM</DIV> <DIV style=3D"FONT: 10pt arial"><B>Subject:</B> antioxidants</DIV> <DIV><BR></DIV> <DIV><FONT color=3D#000000 size=3D2>Had some problem with first post, = here's a=20 repeat.</FONT></DIV> <DIV><FONT color=3D#000000 size=3D2></FONT> </DIV> <DIV><FONT color=3D#000000 size=3D2> <DIV> <DIV><FONT color=3D#000000 size=3D2>Have recently attended a = presentation on the=20 above by a</FONT></DIV> <DIV><FONT color=3D#000000 size=3D2>Prof Halliwell. I would like to = run it and=20 related queries, </FONT></DIV> <DIV><FONT color=3D#000000 size=3D2>by the list for opinions. = Superoxide anion=20 damage to DNA</FONT></DIV> <DIV><FONT color=3D#000000 size=3D2></FONT><FONT size=3D2>was tracked = by tracing 8OH=20 deoxy Guanine, in urine.</FONT></DIV> <DIV><FONT size=3D2></FONT> </DIV> <DIV><FONT size=3D2>1 Subjects were given a = commercially=20 available antioxidant,</FONT></DIV> <DIV><FONT size=3D2>8OH dG was found in increased levels and study=20 terminated</FONT></DIV> <DIV><FONT size=3D2>at 2 weeks.</FONT></DIV> <DIV><FONT size=3D2></FONT> </DIV> <DIV><FONT size=3D2>2 Same set of subjects were = given 500gm of=20 raw tomatoes,</FONT></DIV> <DIV><FONT size=3D2></FONT>{once a day} <FONT size=3D2>8OH dG levels = decreased and=20 leveled off. Study terminated.</FONT></DIV> <DIV><FONT size=3D2></FONT> </DIV> <DIV><FONT size=3D2>3 When asked, he said that = persons exposed=20 to hyperbaric</FONT></DIV> <DIV><FONT size=3D2>oxygen showed an initial increase in degradative = products,=20 but levels</FONT></DIV> <DIV><FONT size=3D2>gradually decreased to pre-exposure levels. Time = line=20 not</FONT></DIV> <DIV><FONT size=3D2>mentioned.</FONT></DIV> <DIV><FONT size=3D2></FONT> </DIV> <DIV><FONT size=3D2>Aside, my questions are:-</FONT></DIV> <DIV><FONT size=3D2></FONT> </DIV> <DIV><FONT size=3D2>Commercially available preparations of SOD, = Catalase=20 and</FONT></DIV> <DIV><FONT size=3D2>Glutathione Peroxidase don't make it the cellular = level=20 because</FONT></DIV> <DIV><FONT size=3D2>of protease action and stomach pH, and are = therefore not=20 worth</FONT></DIV> <DIV><FONT size=3D2>crap?</FONT></DIV> <DIV><FONT size=3D2></FONT> </DIV> <DIV><FONT size=3D2>If I'm planning preventive anti-ox therapy of vit = E, C,=20 Selenium etc</FONT></DIV> <DIV><FONT size=3D2>do I plan according to Ox Tox % per dive day or = cumulative=20 ox tox</FONT></DIV> <DIV><FONT size=3D2>per dive mission, or should I just go mega dose or = saturation?</FONT></DIV> <DIV><FONT size=3D2></FONT> </DIV> <DIV><FONT size=3D2>Any feedback on pine bark extract?</FONT></DIV> <DIV><FONT size=3D2></FONT> </DIV> <DIV><FONT=20 size=3D2>Omar</FONT></DIV></DIV></FONT></DIV></BLOCKQUOTE>< /BODY></HTML> ------=_NextPart_000_0282_01BFB50D.3D1A4F80-- -- Send mail for the `techdiver' mailing list to `techdiver@aquanaut.com'. 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