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Date: Wed, 25 Sep 1996 00:54:26 -0700 (PDT)
From: Peter Heseltine <heseltin@hs*.us*.ed*>
To: "Dunk, John" <screwloose@ne*.co*>
cc: techdiver@terra.net
Subject: Re: Side effects of Lariam
John

On Wed, 25 Sep 1996, Dunk, John wrote:

> On Tue, 24 Sep 1996 23:42:43 -0700 (PDT), you wrote:
>
> It would certainly seem that doxycycline is a much better choice

Well, I am not sure that the adverse reaction rate is necessarily *much*
less than the quinolones. I jus think that it is a more effective malaria
prophylaxis

> understood.My info does relate that the incidence of G.I disturbance
> is high,perhaps as much as 39%,

True, but at a dose of 100 mg/day in an adult, GI intolerance is
rare. Much less than with other tetracyclines.

> distress,and recommends avoiding this dosage.Also,use of sunblocks
> seem to have only limited efficacy in preventing the
> photosensitivity;

I find that if people use a *complete* block - factor 20+ - with UVB as
well as UVA effect, I have never seen a photosensitivity reaction.

     *******************************************************************
     * Peter Heseltine, M.D., F.A.C.P.                                 *
     * Professor of Medicine                                           *
     * University of Southern California        LAC+USC Medical Center *
     * Tel: 213/226-6705                       1200 North State Street *
     * Fax: 213/226-2479                    Los Angeles, CA 90033-1084 *
     * Eml: heseltin@hs*.us*.ed*                                   USA *
     *******************************************************************


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