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From: Robert Chambers <rchambers@su*.ne*>
To: "techdiver@terra.net" <techdiver@terra.net>
Subject: RE: Free radicals in Biology and Medicine
Date: Thu, 21 Mar 1996 07:58:02 -0400
Don't stop now, give us more information.  I've been making sure I take =
my vitamins at least a couple of days before I make a dive.  They are of =
the antioxidant variety.  I hope this wont end up being a problem.


Robert Chambers
Barbados
West Indies.

----------
From: 	John Gibbons[SMTP:jgibbo@ph*.lo*.ac*.uk*]
Sent: 	Wednesday, March 20, 1996 1:10 PM
To: 	techdiver@terra.net
Subject: 	Free radicals in Biology and Medicine

I came across a good book for those peole who really want to get down to =

the nuts and bolts of what oxygen does to mammalian organisms. This book =
is=20
not for the faint hearted but does give a comprehensive account of what=20
free radicals are involved in.=20

Its title is: Free radicals in Biology and Medicine 2nd ed. 1989, =
published=20
by Oxford University press, Author Halliwell and Gutteridge.=20

It is now seven years out of date but would be good for those interested =
in=20
O2 tox. It had a nice little section on the possible adverse effect of =
high=20
concentrations of Vit C for those folks who like to overindulge. In the=20
presence of H2O2 it can produce hydroxyl radicals via the Fenton =
reaction=20
(depending on conc. and a few other factors)and can stimulate iron=20
dependent peroxidation of lipids.

Just thought someone might be interested.

J Gibbo

John M. Gibbons                       0171-793-1101 Home
Univ. London School of Pharmacy       0171-582-6561 Fax
Dept. of Pharmaceutical Chemistry     0171-753-5800 Wk ex 4882
jgibbo@cl*.ul*.ac*.uk*            or
jgibbo@ul*.ac*.uk*
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