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Date: Wed, 20 Mar 96 17:10:17 GMT
From: "John Gibbons" <jgibbo@ph*.lo*.ac*.uk*>
To: techdiver@terra.net
Subject: Free radicals in Biology and Medicine
I came across a good book for those peole who really want to get down to 
the nuts and bolts of what oxygen does to mammalian organisms. This book is 
not for the faint hearted but does give a comprehensive account of what 
free radicals are involved in. 

Its title is: Free radicals in Biology and Medicine 2nd ed. 1989, published 
by Oxford University press, Author Halliwell and Gutteridge. 

It is now seven years out of date but would be good for those interested in 
O2 tox. It had a nice little section on the possible adverse effect of high 
concentrations of Vit C for those folks who like to overindulge. In the 
presence of H2O2 it can produce hydroxyl radicals via the Fenton reaction 
(depending on conc. and a few other factors)and can stimulate iron 
dependant peroxidation of lipids.

Just thought someone might be interested.

J Gibbo

John M. Gibbons                       0171-793-1101 Home
Univ. London School of Pharmacy       0171-582-6561 Fax
Dept. of Pharmaceutical Chemistry     0171-753-5800 Wk ex 4882
jgibbo@cl*.ul*.ac*.uk*            or
jgibbo@ul*.ac*.uk*

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