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Date: Thu, 29 Feb 1996 04:40:46 -0800
From: iantdhq@ix*.ne*.co* (IANTD )
Subject: Re: DAN Article
To: Robert Wolov <wolov@hi*.co*>
Cc: cavers@ge*.co*
Cc: techdiver@terra.net
Robert,
If you check on sudafed it states that sudafed has a SIDE (not 
overdose) effect of seizures, apprehension, aniziety etc. sounds like 
other things we talk about .

We have circumstantical evidence that it has been involved in a couple 
of fatalities. We published this about three years ago. In addition we 
had numerous reports from folks who had problems while using sudafed. 
Both Patti and I have had a bad experience on dives wgen using sudafed. 
Jim Lockwod had a rather bad situtation on deco on a dive using 
sudafed. He almost toxed in a rather safe zone. With his background it 
had to be the sudafed.

I find it hard to beleive that anyone would choose to use sudafed when 
this published side effect Look it up in your PDR .
Tom
You wrote: 
>
>>I am aware of anecdotal evidence for a link between 
>>pseudoephedrine and O2 toxicity.  If there is any empirical evidence 
I 
>>would appreciate this information.  Thanx, Pete
>
>
>Good to my threat, I just checked the Toxline database at NIH to see 
if 
>there's any articles discussing any synergistic effects between 
sudafed 
>and O2 toxicity...nada...nothing listed. 
>
>That doesn't mean there's nothing out there, only not in the journals 
>cataloged by the National Library of Medicine (which isn't 
everything). 
>Their system only goes back to about 1966.
>
>The real problem with sudafed (or any antihistamine for that matter) 
and 
>diving is that it wears off in a "hostile" environment leaving you 
worse 
>off than if you were on the surface.
>
>If you follow my reasoning, people take antihistamines to help keep 
their 
>sinuses and eustasian tubes open. Now take a diver with say just a low 

>grade marginal head cold or just inflammation. He pops a sudafed and 
goes 
>for a dive.(dumb move , but this is hypothetical after all) 
>
>He's just open enough to partially clear, but as he is exposed to 
deeper, 
>colder water, the eustasian tubes begin to reflexively shrink down 
from 
>the cold (they can shrink closed by almost 2/3's I'm told by my diving 

>med friends) from what they were on the surface. Now the drug is 
>metabolizing and starts to wear off (possibly at a faster rate than 
the 
>surface). What little clearing benefits there were are wearing off. By 

>now the diver is at depth and pressurized. He's got to ascend sometime 

>but now he's a set-up for a reverse squeeze since he's relatively 
>overpressurized behind closed eustasian tubes.
>
>As if that's not bad enough, you want to throw in O2 toxicity for good 

>measure?...You're a tough guy, Pete!  ;-)
>
>Sorry the lit search wasn't more productive.
>
>Take care.
>
>Robb Wolov
>
>--
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>

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