If you are breathing a high PO2, and ascend rapidly to the point where the PO2 drops significantly, it is possible to get a "reversed" O2 gradient. O2 can start to move out of your body and you can become hypoxic. This is what happens to breath-hold divers as the PO2 in their lungs falls during ascent after a long dive: shallow-water blackout. The key is that the the PO2 has to drop below thw .16ata or so threshold...as in the long-staying breath hold divers ascent. I don't understand how it would work when changing from one breathable medium to another, as in an ascent from any dive. Bernie Woolfrey
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