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From: <kirvine@sa*.ne*>
Date: Tue, 30 Nov 1999 09:46:58 -0500
To: Gerard Stainsby <gvs@ne*.ne*.au*>
CC: WILLIAM GEARMAN <gearman_1@ya*.co*>, techdiver@aquanaut.com
Subject: Re: Another Incomplete Study
Gerard, this is not a WKPP or DIR issue - it is a fact of life. Yes, I
do require my divers to get tested, but then I am not an idiot, and do
not need to put my hand on the stove to know it is hot. Obvious is good
enough for me.

You guys argue this while I don't worry about it .


Gerard Stainsby wrote:
> 
> Asbestos drysuit on...  :-)
> 
> WILLIAM GEARMAN wrote:
> >
> > Just FYI everyone.
> >
> > The below was released today.
> 
> Which do you mean, the Reuters article, or the
> paper/presentation to which the Reuters article
> is referring? (Which you haven't referenced and
> presumably didn't attend.)
> 
> > Again, the experts
> > have conveniently left out numerous variables.
> 
> Ah, so the Reuters journalist/s who've downgraded
> any actual scientific content to the level that
> Joe Average reader can understand and that you can
> criticise have left out numerous variables, so you
> presume that there were none in the source presentation?
> 
> > Even so, it could raise some interesting
> > discussions.
> 
> True, but I expect it'll turn into a flame war
> like most other opportunities here.
> 
> > It sure would have been nice if
> > they had done this study with data with other
> > types of gas media and differential subject
> > groups such as WKPP. Wonder how many stokes were
> > in the study?
> 
> Probably all of 'em. (that is, many or all of the
> people studied may have been strokes, not that all
> the strokes in the world would have been studied!) :-)
> 
> Partly this will be due to a sampling bias.
> 
> 1. most of the world doesn't do technical diving at
> all, let alone DIR technical diving. If you stand on
> a street corner and shout out "20 bucks if you're a
> diver and will lie still for a brain scan", you'll
> get PADI, not WKPP.
> 
> 2. Non-strokes are usually? often? people who have
> graduated through strokedom, once they've been exposed
> to the light. If a person in their early diving days
> gets enough subclinical hits (perhaps because of a PFO)
> they're unlikely to progress to technical diving or DIR,
> meaning that if you study DIR divers you're more likely
> to find non-PFO people.
> 
> 3. If Knauth has studied people who have had a documented
> hit, we have another sampling bias: the WKPP won't
> conveniently generate enough brain lesions to study,
> at least that we know of.
> 
> The sampling method would have been presented by Knauth
> in the paper, but it's not really his/her fault that
> Reuters hasn't given it in their release.
> 
> Let's face it, if you wanted to make the diving world
> safer (saving neurones or lives, whichever) for those
> great PADI masses who do air in warm water to 12m
> (18m on an adventurous day) there are two approaches:
> 
> - get 'em to do DIR (desirable, but pretty unlikely, and
> watch the price of heliox as demand rockets) or
> 
> - get 'em to dive conservatively, and identify divers
> at special or increased risk, & devise strategies to
> minimise extra risk in these people.
> 
> > BigVon, did you participate? ;-) Might explain
> > his attitude and mind set. eeh, George?
> 
> Cheap shot & brown-nosing in two lines. Very economical.
> 
> >
> > >"Monday November 29, 2:20 pm Eastern Time
> >
> > Scuba diving dangerous for heart defect
> > sufferers
> >
> > CHICAGO, Nov 29 (Reuters) - Scuba diving can be
> > dangerous for
> > the one out of every four people who have a
> > common heart defect that
> > makes them susceptible to decompression sickness
> > and brain lesions,
> > researchers said on Monday.
> >
> > The heart condition, called patent foramen ovale
> > (PFO), is an opening
> > in the connection between the left and right
> > sides of the heart. Those with PFO can have
> > relatively harmless skin rashes or develop
> > serious neurological problems such as vertigo or
> > even paralysis.
> >
> > During dives, inert gas bubbles that form in the
> > bloodstream can bypass the filter in the heart of
> > PFO sufferers that would normally send the
> > bubbles to the lungs.
> >
> > The bubbles then travel through the body, causing
> > decompression sickness, and into the brain
> > where they can create lesions, said Michael
> > Knauth, a radiologist at the University of
> > Heidelberg Medical School in Germany, who
> > presented his findings to the annual meeting of
> > the
> > Radiological Society of North America in Chicago.
> >
> > Decompression sickness, which can be fatal,
> > occurs when gas bubbles are released into tissue
> > after a too rapid decrease in air pressure
> > following a stay in a compressed atmosphere --
> > such
> > as under water.
> >
> > In cranial examinations of 88 scuba divers,
> > Knauth said four of five divers with PFO were
> > found to have several brain lesions each. Brain
> > lesions were rare among non-PFO divers.
> >
> > ``It is unclear whether the brain lesions can
> > cause long-term problems, but common sense would
> > tell you if you have enough of them and they're
> > in the right places, they could cause problems,
> > such as memory disturbances or difficulty
> > concentrating,'' Knauth said.
> >
> > In another aspect of the study, 19 out of 24
> > divers who had unexplained diving incidents,
> > despite
> > following the rules of decompression such as
> > descending and ascending slowly, turned out to
> > have PFO. Some also had large brain lesions.
> >
> > ``Divers with PFOs should reduce the depth they
> > are descending to, not stay deep too long,
> > ascend slowly, increase the time they spend above
> > water between dives and avoid several
> > descents during one dive,'' Knauth said.
> >
> > Knauth suggested prospective divers get tested
> > for PFO before being certified to dive."<
> 
> Knauth is citing this on traditional investigational
> medicine grounds (and presenting to a group of
> investigational medicine specialists).
> 
> a) if there's a group at risk (seems to be divers
> with PFO) and
> b) if there's a test to identify this group then
> c) if you do the test you'll identify the group
> at risk, and can
> d) take steps to reduce the risk. At the very least
> you'll have a group of divers who know that they
> have an otherwise fairly benign condition which might
> influence the way they (should) dive.
> 
> (This may seem very obvious but some of the readership
> seems to have/claims to have legal training, and it's
> worth noting that (investigational) medicine is a
> discipline based on scientific principles and truth
> based on observation and logic, rather than law where
> the "truth" is based on what you can persuade a jury.)
> 
> 
> > Duh? That's a no brainer!
> 
> Why?
> 
> The fact that it is probably impracticable on the
> basis of cost, compliance, availability of tests
> and so on doesn't mean that in principle it's not
> a reasonable thing to suggest.
> 
> Since I didn't attend the presentation, I don't know what
> test Knauth is proposing. A reasonable test is transthoracic
> echocardiography with bubble contrast, looking for
> microbubbles in the systemic circulation after an intravenous
> injection of agitated saline. Possibly a better test would
> be transoesophageal echocardiography, which usually permits
> better visualisation of some of the relevant cardiac structures.
> It requires fasting beforehand, intravenous sedation, a trained
> echocardiologist with an assistant, about half-an-hour and
> probably _wouldn't_ fit into the $70 or so (around here)
> fee for a standard diving medical. Around here an echo machine
> with a TOE probe costs ~ $300K and they're mostly busy doing
> tests on actual patients with actual sick hearts.
> 
> If Knauth has a better test he (she?) might be onto something
> worthwhile.
> 
> >
> > Sincerely, William
> 
> Cheers,
> 
> Gerard Stainsby
> (in a funny sort of mood today, sorry, don't know why)
> 
> --
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