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Date: Tue, 24 Aug 1999 14:41:18 +1000
To: techdiver@aquanaut.com
From: Phil Davies <P.Davies@un*.ed*.au*>
Subject: PFO/DCS
Another piece of information dealing with one of the studies I posted
regarding PFO and DCS. One of the studies citing an increased rate of
cerebral DCS in divers with PFO (Germonpre et al 1998) was  actually
carried out using funds from a grant from Divers Alert Network Europe.
Strange that such an organization supports such important work but doesn't
follow through when the results suggest that a substantial number of divers
could avoid serious injuries by simply being aware of a PFO.  Perhaps
someone from DAN is reading this and can explain why.  As George strongly
points out they still could have told divers of the risks involved.
 I should also point out that in most patients during the normal cardiac
cycle, no significant shunt or blood flow occurs from the right to left
atria (even if a PFO is present as the right atrial pressure is normally
lower than the left). However in some patients, reversal of the pressure
gradient between the atria may occur-if you have a PFO then a signficant
shunt or flow occurs.  Clinically if a left-to-right shunt occurs at rest
then the term PFO is not used but instead it is referred to as a "atrial
septal defect" (ASD).  While ASD is mostly asymptomatic,  it is an accepted
contraindication for sports diving.  Yes thats right they bar you from
diving.  Why they don't see PFOs as a problem eludes me given that the type
of PFOs we are talking about are really minor versions of a ASD coupled
with the fact that a significant proportion of divers may experience an
increase in right atrial pressure and open the PFO.  Given the consequences
of paradoxcial embolism of nitrogen (or any other gas) bubbles flowing
through the PFO and into the cerbral vasculature has disasterous effects it
is bizzare no one seems to take this seriously.  Perhaps  people are
uncomfortable with the fact that a condition they have no control over
creates a situation where the sport they love so much may seriously maim
them.  Sticking your head in a bucket is not the answer.
As George has pointed out valve defects aren't the same thing as a
inefficient valve doesn't allow blood to flow from the right to the left
atria except by allowing it to travel through the lungs which are a natural
bubble trap.

For those interested we all start out with a PFO.  This is because the
foetus during development is not breathing hence its lungs are collapsed
and therefore circulation through the pumonary circulation has a high
resistance. So flow will occur thru the PFO into the left atria.  On birth,
the first breath of air inflates the lungs causing a reduction in pulmonary
resistance and the PFO closes.  Functional closure occurs within hours and
complete fusion usually takes some months.  In some people this fusion of
the PFO is incomplete and a small opening between the left and right atria
remains throughout life.

Anyway I think I've exhaustied this subject and will go back to lurking
again.  Hope this information helps the list understand a subject that the
agencies seem to ignore despite its lethal implications.

Phil Davies


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