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From: "Robert Lockard" <rlockard@ho*.co*>
To: techdiver@aquanaut.com
Subject: On Gassing Question
Date: Tue, 20 Jan 1998 10:40:18 PST
OK guys, I seem to be having a "Blond Moment" on this issue.  I am not a 
chemist, or a physiologist.  So I am having a difficult time 
understanding the relationship of mol weight to solubility.  That is if 
there is any relationship.  And the relationship to narcosis. 

When I look at the quantity of a gas in blood at 1ATA, vs. % of gas in 
air, vs. Mol.Wt, I get confused on the issue of argon in the blood.  
PPAg would be .00934 ATA at 1ATM, why then so much Ag in the blood?  And 
look at Ne, there is .00002% Ne in the blood with 9.178 ml/l. 

First off Buhlmann's book does not say whether the quantities or artial 
blood or vascular blood.  I believe from the O2 number that the blood is 
artial.

Some base knowledge: 

1. O2 is metabolized and CO2 is generated as a product of 
matabilization.  Therefore; the quantity in blood will change with 
respect to time, work effort, and what part of the circularity system is 
being measured.

2. The other gases, He, Ne, N2, H2, Ag remain relatively constant in air 
at 1ATA.

3. Other tissues are not in this discussion.  I am trying to simplify 
the puzzle.

GAS 	QTY ML/L BLOOD	%AIR	     MOL.WT.	Narcotic/Toxic
O2	23.252	        0.29948	     31.999     Toxic and Narcotic?
CO2	483.565	        0.00031	     44.010     Toxic
He	8.686	        0.000005      4.0026    HPNS
Ne	9.178	        0.00002	     20.183     ?
N2	12.183	        0.78084	     28.013     Narcotic
H2	14.705	        0.0000005     2.0159    ?
Ag	25.660	        0.00934	     39.948     Narcotic

Questions:

1. Is there any relationship between Mol.Wt. and solubility?  If there 
is I can not see it here.

  1.a. Is there a standard measure of solubility?

2. Is the high solubility of argon perhaps the reason it is so narcotic?  
With these numbers, I can not determine if the PPAg is increased, how 
much will Ag will be absorbed to achieve equilibrium.

  2.a. Does argon bind to anything in the blood, or does it just take up 
space? How about the other "inert" gases?

3. There is a relationship between Mol.Wt. and narcotic.  By looking at 
these numbers the assumption is Ne and H2 are Narcotic.  I have not been 
able to find references to Narcotic effects of these gases.

4. Can someone direct me to a reference, i.e. Anastasia medicine that 
may dive into the effects of these gases on the body?


Robert P. Lockard
===============================================================
rlockard@ho*.co* (preferred)
lockardr@ao*.co* (full of spam)
540.898.3632 (home office)
540.842.6343 (cell)
202.685.1629 (work site)

"Life is a daring adventure or nothing at all."
 Helen Keller


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