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Date: Sat, 2 Mar 1996 12:57:40 -0800 (PST)
From: Eric Maiken <ebmaiken@ea*.oa*.uc*.ed*>
To: Dan Volker <dlv@ga*.ne*>
cc: techdiver@terra.net
Subject: Re: gas exchange rates as they effect nitrogen saturation

Dan:

You point out some important differences between the *fit* and *otherwise* 
that likely play fundamental roles in decompression modeling.

Considering much greater perfusion of blood through athletic tissue (due 
to increased vascularization, strong heart, clean plumbing,etc) your idea 
about rapid ingress/egress of inert gas to tissue seems reasonable and is 
incorporated in setting tissue halftimes by Buhlmann and others (Q-dot) 
In using the "rate" equations to calculate tissue tension. The idea being 
the better the perfusion, the shorter the half-time.

Arguments based on diffusion need to consider the solubility of gas in 
tissues (how much gas is soaked up from the bleood) , the distance between 
blood vessles (characteristic distance gas moves), and the diffusivity of 
the gas (how fast the gas moves).

You point out the "Pinneped" model: Q: Why don't Walruses get bent? 
Typical A: They shunt blood flow away from blubber to critical organs.

> 
> One list member has suggested to me that the heavily overweight divers may 
> actually absorb less nitrogen then currently assumed (based on Nitrogen 
> solubility in fat)

Doesn't seem to make sense. First, apearences aside, divers aren't walruses.

I don't recall who said what, but....The solubility of all gasses that 
you will ever *reasonably* inhale (Unless you acytelene weld inside a dry 
habitat) is much greater in oils than blood. Nitrogen, Helium, Argon, you 
name it; If blood moves these gases to fatty tissue, two-to-five times as 
much will be soaked up compared to lean tissue


> because of the extremely poor vascularization of fatty 
> tissues (this means slower in and MUCH SLOWER OUT), which would place 
> diffusion rates in these tissues at well below what will occur in areas with 
> well developed capillary beds..


For Helium: Diffusivity is big, not very soluble in fat or lean tissue, 
but pressure gradient between tissue and -bubbles- is big. (Note, however, 
the pressure grad. between -blood- and tissue will tend to fall rapidly)

For N2 and O2: Solubility is much greater in fat compared to water/blood 
(about 5 times), so potentially, fatty tissues can store a lot of gas IF the 
blood transports the gas to the tissue

If you believe that reducing total bubble volume reduces severity of 
dcs symptoms, than you can also argue for fitness. 

Both statistical and bubble models use a "critical volume" hypothesis to 
create decompression schedules. You will always get some bubbles, unless you 
are de-nucleated (as George probably is from lots of DEEP dives).... The 
trick is controlling both the number and size of growing bubbles. For 
instance, you point out that for a supersaturation model, deeper stops 
might be needed by the *fit* because of large *fast* tissue tensions. 

If you consider that bubble growth depends fundamentally on the gradient 
of partial pressure between tissue and bubble, (and the Diffusivity
-Solubility product of the gas, etc, etc), then deep stops look good.

But, perhaps if you trace out the time history of bubbles formed 
early in the deco schedule, you will find that a lean person can tolerate 
the formation of a greater population (number) of growing bubbles, 
because in the deco/surface interval phase of the dive there is less 
dissolved gas in tissues to help the bubbles grow (due to efficient 
out-gassing AND lack of bulk). 

I'm just being the devil's advocate here-- I think deep stops are cool.

Consideration should also be given to otherfactors that tend to keep 
high internal pressure inside bubbles (to help squeeze gas out into tissue). 
Tissue *squishy-ness* (compliance) is important. Big bubbles can't form 
easily in tight tissue. But, on the other hand, *kilo* style power intervals
as you recommend for gas consumption (and good performance in 200' deep 
criteriums around a wreck) may generate bubble nuclei through 
tribonucleation, hence increasing your *population* of growable bubbles. 

There's lot's going on here that can sway the conversation to *fit* and 
*otherwise,* but its 75 deg. here in LA, and I'm going out for a ride....

As a curve ball: The oxygen *window* roll-over (the point where dissolved O2 
can start to *load* tissues) will also depend on the O2-carrying capacity of 
the blood (more RBCs if altitude trained, for example). This would be at 
high-enough ppO2, where deco would be the least of your problems though).

Regards, 


_____________________________________________________________
Eric Maiken                    email: ebmaiken@ea*.oa*.uc*.ed*              
Dept. of Physics                   o: 714 824-6621   
U. of California                 fax: 714 824-2174
Irvine, CA 92715-4575



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