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Subject: Re: DAN Article
Date: Thu, 29 Feb 96 13:30:10 -0000
From: Robert Wolov <wolov@hi*.co*>
To: <kens@uf*.ed*>, "IANTD " <iantdhq@ix*.ne*.co*>, <cavers@ge*.co*>,
    
>Also I believe the US Navy diving manual documents the correlation 
>between pseudophrene (sp?) and CNS O2 toxicity. 

I checked out the Navy Dive Manual and must confess I haven't found a 
reference yet to O2 toxicity and use of Pseudoephedrine-sudafed(the NDM 
doesn't have the greatest index in the world though) but I did see 
something interesting which ties in with the recent discussions on this 
list on physical conditioning and diving.

On pages 3-20 to 3-21 in the chapter on underwater physiology the NDM 
states that at PPO2's of 02. - 0.6 atm there are no toxic effects 
regardless of duration of exposure. From 0.6 to 1.6 atm exposures from 
"days to hours" lung toxicity may occur. At 1.6 atm and greater you get 
CNS symptoms before lung symptoms. But here's the clincher...

"The susceptability to CNS oxygen poisoning varies from person to person 
and that a major contributing factor is the presence of a high pCO2 from 
either "a contaminated gas supply or as a consequence of heavy exertion 
or in adequate ventilation".

Might this mean that the aerobically conditioned diver is *less* 
susceptable to the effects of O2 toxicity? Sounds like it. Do we have any 
pulmonary physiologists in the audience to help me on this one? DAN?


Robb Wolov 

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