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From: <john.r.strohm@BI*.co*>
Date: Mon, 11 Dec 1995 19:38:00 -0500 (EST)
Subject: Re: More: on Antioxidants
To: 73467.2574@co*.co*
Cc: techdiver@terra.net
>double-blind studies would be wonderful. But I would even settle with
>studies on
>any healthy HUMAN that does NOT have a Vitamin-E deficiency.

The problem with that is YOU CAN'T DO THE STUDY.

You have to start with a baseline of O2 toxicity hits vs. time and depth
and ppO2.  If you insist on HUMAN experimental data, you can only get this
baseline by putting HUMAN divers in O2 tox situations and measuring the hit
rates.  THIS IS ETHICALLY UNACCEPTABLE; it is too easy to kill your HUMAN
experimental subjects.

Once you have that baseline, you then have to start feeding more divers
antioxidants and then putting them into the SAME O2 tox situations, and
measuring the hit rates.  THIS IS JUST AS UNACCEPTABLE; YOU ARE RUNNING THE
SAME RISK OF KILLING YOUR HUMAN SUBJECTS.

This is why we do animal studies, for crying out loud.

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