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> There is NO evidence to indicate that the effective dose, suggested >by Mr. Hunscuker of 800 mg every 4 hours would be any more effective to >that end than that of 600 mg/day. We use it every 4-6 hours of IN WATER time. Black et al. seemed to run with the idea that we take this much every day for our own grins and giggles. Once this subject began it ran away with speculation on what we actually do. I was far to busy at that time to interject any corrections. Even on our longest dives we are around 2400 mg/24 hr period. With thousands of hours of actual gas diving we have found by experience that this is beneficial to us. Over the years I have attempted to get many different research oriented organizations to come and study us; the only one that has taken the time to learn from what we are doing, for other purposes, is the US Navy. We are beyond what DAN is interested in by there own admission, at our last presentation to UHMS, most appeared to not believe us, those that were interested have fallen by the wayside. The physiology aspect of what we do takes a back seat, unfortunately. > Lower doses have far less side >effects obviously. Combination of aspirin and ibuprofen as indicted by >Grogan, is definitely NOT necessary. In fact, its doing a disservice. >Aspirin blocks a backup clotting mechanism which depends on the blood >platelets, and leaves little protection against bleeding if used in >combination with other similar drugs. Hunsucker also suggests doses up >to 1.2 grams "used for pain relief in 200mg tablets and prescribed in >800/1200mg strength" which suggests some SERIOUS pain. That type of >pain during diving, would suggest the need for OTHER addressing. I was describing the drug I was NOT referring to pain during diving. >With >respect to inflammation, anti-inflammatory drug dose is dependant on >severity of inflammation. More importantly, inflammation from what, and >how severe is the inflammation? Inflammation from spending several hours at 300', moving dozens of bottles and several scooters around, bubble formation, etc, etc. This is done as a purely preventative step. > Further, ibuprofen has NO, not even >possible, benefits to free radical elimination as suggested. I would >argue that the latter is subjective on the part of Mr. Hunsucker and it >does NOT reflect scientific fact. Here you are correct. This was mentioned to us years ago and is something that I have not taken the time to examine. We do not count on this as we take more aggressive steps in the antioxidant area. > Unless Mr. Hunsucker has study in >hand to suggest differently, it would appear as subjective guessing at >best, as to his suggested dose time relation / relevance / benefits etc. >to diving. I do not have studies, only testimony from a handful of divers with thousands of hours in decompression between us. I might try your suggestion of a lowered dosage on my next 300' dives, if I do, and have success, we might change our approach. > I am however, interested at the hypothesis behind the particular >exacting doses suggested, if in fact they are based on something other >than conjecture. Dosage came from our contacts with US Navy Hyperbarics as did the combination of ASA. That may have been because ASA has been used in diving for many years. Sincerely, Scott Hunsucker -- Send mail for the `techdiver' mailing list to `techdiver@aquanaut.com'. Send subscribe/unsubscribe requests to `techdiver-request@aquanaut.com'.
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