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Michael, nobody listens to an idiot like Back anyway. We use NSAIDS successfully all the time. Unlike that asshole I get my protime checked along with everything else. This dumfuck is not in our league, and talking to him his like having a14 year old at the dinner table. Back of the hand is all he will ever get from me or anyone else. -----Original Message----- From: Michael Seeley <mseeley@po*.ne*> To: techdiver@aquanaut.com <techdiver@aquanaut.com> Date: Wednesday, June 14, 2000 2:40 PM Subject: HEADACHES WHILE DIVING > >God almighty you guys must bleed like >hell if you ever cut yourself (ibuprofen prolongs bleeding time just >like aspirin, not to mention the effects it has on your stomach). > > >Just to set the record straight, aspirin and ibuprofen do NOT affect >bleeding and platlets in the same way. Below is a brief explaination >of the diference. If anybody is really that interested I can send >the whole article (with references). Hopes this helps explain. >Thanks and Safe Diving >Mike Seeley > > >NON-STEROIDAL ANTIINFLAMMATORY AGENTS EFFECTS ON PLATELET FUNCTION >RESPONSE: >Nonsteroidal antiinflammatory agents (NSAIAs) interfere with platelet >aggregation and bleeding time due to inhibition of prostaglandin (PG) >synthesis. NSAIAs inhibit cyclooxygenase, an enzyme that catalyzes >synthesis of prostaglandins from arachadonic acid. The net result of >this action is a reduction in thromboxane A2 production and release >resulting in reduced platelet aggregation. Collagen-induced >aggregation is inhibited by NSAIAs because this effect is dependent >on thromboxane A2 formation (Schafer, 1995; Anon, 1979; Hirsh, 1979). >Differences in the effect on platelet aggregation and bleeding time >exist between aspirin and NSAIAs. Aspirin irreversibly inhibits >platelet aggregation but NSAIAs reversibly inhibit platelet >aggregation for the duration of the drug effect in the circulation. >While aspirin increases the bleeding time by as much as two times the >normal value, NSAIAs increase the bleeding time but it usually >remains within the upper limit of normal (Schafer, 1995). > >-- >Send mail for the `techdiver' mailing list to `techdiver@aquanaut.com'. >Send subscribe/unsubscribe requests to `techdiver-request@aquanaut.com'. > -- Send mail for the `techdiver' mailing list to `techdiver@aquanaut.com'. Send subscribe/unsubscribe requests to `techdiver-request@aquanaut.com'.
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