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Date: Sun, 20 Feb 2000 08:18:12 -0600
To: Esat Atikkan <atikkan@ya*.co*>, techdiver@aquanaut.com
From: Scott Hunsucker <swhac@pc*.gu*.ne*>
Subject: Re: Oxygen (the quick and dirty version)
Esat,

>It is possible to exceed, w/i reason, the 'safe pulmonary dose' guidelines 
>w/o out long term ill effects.  It is just a matter of the amount of the 
>discomfort one is willing to put up w/.

We have now changed procedures and have extremely low, if not none at all, 
symptoms of pulmonary toxicity.

>(Paranthetically the jury is out on the true long term effects - the 
>carcinogenic effects of free radicals).
On this I will agree.  However, science thinks that everything save for sex 
causes cancer!  ;-)

>It is also possible to change the threshold of the ill effects of HBO or 
>prolong the latent period w/ mediactions that scavenge free-radicals, the 
>agents currently held to B causal in oxtox.  Nutrients additives have also 
>been suggested.
All very important and all added to our regiment.

>Still, it is also incontravertible that many if not all divers, WKPP 
>divers included, do report 'chest burning' when exposed to protracted deco 
>w/ high ppO2.
We have handled/reduced this problem with the addition of 25% He to all 
deco gases, except for O2.  Easier to breath, soothing effect on possibly 
irritated tissue.  Prior to this, on shorter dives, we would have 
reports/symptoms of pulmonary toxicity.  For this type of diving (BT times 
common in the WKPP, not your average BT) it is sort of like mask rings, and 
bubbles, signs that you have been diving.  After the addition of the He, no 
ill effects.  Pulmonary and other oxygen problems are definitely a limiting 
factor to human performance at pressure.

>Maneouvers like air breaks do ameliorate this but do not show up in the 
>stnd OTU calculations wh/ require a 24 h break before the pulmonary clock 
>is set to 0.  Thus the calc values R artificially elevated relative to 
>actual expo values.
Also true for the CNS calculation given earlier, but this was disclosed by 
us.  We do not know how to calculate with the breaks (yet??).

>New data always becomes available.  The validity of the data depends on 
>not who publishes it but whether it can B reproduced by an independent 
>investigator.  Obviously all the details of the protocols used to generate 
>the data have to B made avialble for that to happen.

I do not know of many that would want to reproduce what we do, but we are 
continuing to do it, and if enough data is ever collected, then perhaps 
there will something for others to work with.
Scott Hunsucker

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