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From: <kirvine@sa*.ne*>
Date: Fri, 24 Dec 1999 06:21:37 -0500
To: PVanscoik@ao*.co*
CC: mjblackmd@ya*.co*, techdiver@aquanaut.com
Subject: Re: N2 Tolerance - disagree
Excellent. I was a far more "experienced" drunk driver than my brother:
he wrecked 9 cars, broke most of the bones in his body, including his
hip, had to have some organs removed, and is in pain all the time now,
and I only wrecked two. The difference: he always drove a Porche or a
Vette, I was a smart boy - I drove my pickup truck with the giant mud
tires and it would not get out of its own way, and I lived on A1A, where
there was no traffic at night back then.

It's a good thing I don't drink now, and it's a good thing they make
helium.

PVanscoik@ao*.co* wrote:
> 
> Dr. Black,
> 
> sorry to disagree.
> 
> one can develop tolerance to alcohol (induction of enzymes to breakdown ETOH)
> one can develop tolerance to many drugs (morphine, etc) requiring greater
> dosages
> one can affect neurotransmitters with SSRI drugs
> BUT all these effects take weeks to develop[and most involve the liver].
> 
> just how would the nervous system adapt to absorption of N2 in the myelin
> sheath? can it alter the action potential? open more ion channels? can it
> alter the number of vessicles of ACH released at the synapse? what nitrogen
> metabolic pathways exist?
> 
> compare  the deep air diver with a functional drunk.
> both can perform routine tasks.
> both are compromised with regard to reaction times, judgement, and complex
> tasks & fine motor skills.
> a novice drunk may fall down walking, an experienced drunk may walk to his
> car & drive home. [God help those on the road.]
> 
> i would love to see some real data - repeat hyperbaric chamber dives on the
> same cohort & test scores. are we debating facts or opinions?
> 
> peteV
> saintpetersburgFL
> 
> --
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