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From: "Eric Maiken" <emaiken@go*.co*>
To: <:CHKBOONE@ao*.co*>
Cc: <techdiver@aquanaut.com>
Subject: Oxygen Windows 95 and 98
Date: Sat, 25 Jul 1998 22:30:14 +0900
Hey Chuck:

I'm at a big disadvantage over here without any deco
references, but here's my diluted memory and opinion of 5+
year old information.... Check out "Metabolism Decreases
With Death" under my name in the archives.

Regarding bubbles in general, they likely don't form in
circulation--they form in tissues. The bubbles in
circulation have busted in to the capillaries.

The short answer to concerns about oxygen bubbles is that
unless you are at a ppO2 of around 2.0, there is likely no
significant oxygen tension in your tissues to drive O_2
bubble growth. Therefore there are no oxygen bubbles (or,
the ppO2 in mix bubbles is near zero).

This is attributed to "inherent tissue unsaturation," or
"oxygen window." Vann and Thalmann give a great picture of
what the O_2 window is in their chapter in "4th ed. The
Physiology and Medicine of Diving." Brian Hills gives a nice
analysis in "Decompression Sickness" too.

As I recollect it goes like this:

You breath in gas delivered at ppMix ~ Pambient. Because of
the ppCO2 and ppH2O in your lungs, the ppMix is reduced
slightly in your lungs. If you are alive, then you
metabolize some of the ppO2 of your mix to ppCO2 -- but,
because CO2 is more than 20x as soluble as O2 in tissue, the
TOTAL tension of dissolved venous gas ~(ppO2 + ppCO2 + ppH2O
+ ppDiluent) is less than ambient pressure. This
difference(gradient) in pressures is the oxygen window.
Venous O2 tension indirectly has a lot to do with inert gas
management through its absence.

Where the oxygen window really makes a difference is on
decompression or recompression. On decompression, TOTAL
Venous tension is less than ambient, TOTAL Tissue tension is
greater than ambient, and TOTAL bubble pressures are
(slightly) greater than ambient.

Consider the 20ft/6m stop on O2 after an air dive. Your
bubbles have a ppN2 ~ 1.7 ata. Your tissues have ppN2 < 1.7
ata that is decreasing with stop time as driven by the
tissue-venous ppN2 gradient. Even tho you are breathing O2,
your venous ppN2 is not 0-- your blood is carrying ppN2 that
was given up by the offgassing tissues. Nonetheless, the
venous ppN2, ppH2O, and ppCO2 are small. So, the total
tension of  dissolved venous gas is much less than ambient
pressure and the oxygen window is wide open. Alternatively,
if you were on air for the 20 ft stop, the ppN2 of the
inspired  gas would be > 1.3 ata and the oxygen window is
slammed shut.

No matter what your mix, if you have bubbles, the O2 window
~(Pambient - Pvenous dissolved gas tension) drives
elimination of the free gas. Bubbles offgas to tissue,
tissues offgas to veins.




_____________________________________________________

Eric Maiken

Green Bell 102
Ogigayatsu 2-8-9
Kamakura 248
Japan

email emaiken@go*.co*
Page  http://www2.gol.com/users/emaiken
Phone (81) 0467 22 2898

_____________________________________________________

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