I don't advocate the the use of any medications with diving. Obviously the more physiologically trying a dive is or could become, the greater the need to avoid extraneous factor that could, at the very least, be unknowns or, in the worst case scneario, be an affector. However, I think classifying pseudoephedrine as an 'upper' may be extrapolation. PE works via the cGMP pathway & is an inhibitor of an enzyme (GCyclase), to the best of my recollection. To invoke a contribution to HP oxtox one has to postulate not only that PE is neurogenic, that its neurogenicity will potentiate a neurogenic oxtox mechanism. I think we may be in the realm of 'data lacks'. Love that word - conjecture. Will look it up, though, But ... Regards Esat Atikkan
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