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Date: Fri, 16 Jun 2000 16:19:09 +0000
Subject: Re: General DCS Information
From: Joel Markwell <joeldm@mi*.co*>
To: John Dunk <screwloo@is*.ne*>
CC: Geoff Kelafant <kelafant@we*.co*>, Techdiver <techdiver@aq*.co*>,
     Cavers
on 6/15/00 7:07 PM, John Dunk at screwloo@is*.ne* wrote:

> As I read this Joel, it doesn't make any claims one way or the
> other about DCS prevention and aspirin. It notes that aspirin
> inhibited a loss of platelets that normally occurs after a
> decompression (in this case saturation) dive. The suggestion is that
> the loss occurs because the platelets attach to microbubbles, which
> may or may not be true, but even if it is, it doesn't tell us whether
> they don't bind because the bubbles are no longer there, or whether
> the platelets are just desensitized to their presence.
> So, I don't think this piece helps.. but I don't have a better one.
> Any body out there that does?

Geoff,

I read it as inconclusive one way or the other. It does indicate that they
seem to think that the "missing" platelets or as they put it, "sequestering
of reactive platelets, possibly by microbubbles," is a clue to how they
think DCS works.

I was trying to look up some of the 16 cited studies in the other post, but
couldn't find any links to the diving related ones. There were only three
that seemed to directly address DCS or diving and I'd love to read those.
Titles mean nothing. It can sound one way and the conclusions reached can be
180 deg. or very cautionary, so only a thorough reading of each cited
reference will do.

Using the right words and calling that proof doesn't quite get it. There is
apparently still a lot more to know. As far as I can see, the usefulness of
using antiplatelet drugs to prevent or help prevent DCS is still an unknown.

Thanks,

JoeL



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